Diagnosis Code


Code Information

Diagnosis Code: E27.1

Short Description: Primary adrenocortical insufficiency

Long Description: Primary adrenocortical insufficiency

The code E27.1 is VALID for claim submission

Code Classification:

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of other endocrine glands (E20-E35)
      • Other disorders of adrenal gland (E27)
        • E27.1 Primary adrenocortical insufficiency

Code Version: 2022 ICD-10-CM


  • Addison's disease
  • Addison's disease due to autoimmunity
  • Adrenomyodystrophy
  • Buccal pigmentation due to Addison's disease
  • Congenital hypoplasia of adrenal gland
  • Congenital primary adrenocortical hypofunction
  • Familial glucocorticoid deficiency
  • Hereditary adrenal unresponsiveness to corticotropin
  • Inherited isolated adrenal insufficiency due to partial CYP11A1 deficiency
  • Melanin pigmentation of oral mucosa
  • Melanosis of mucosa of body orifice
  • Myopathy in Addison's disease
  • Primary adrenocortical insufficiency
  • Primary immunodeficiency with natural killer cell deficiency and adrenal insufficiency

Diagnostic Related Group(s)

The code E27.1 is grouped in the following Diagnostic Related Group(s) (MS-DRG v39.0)
  • Endocrine Disorders With Mcc (643)
  • Endocrine Disorders With Cc (644)
  • Endocrine Disorders Without Cc/mcc (645)

References to Index of Diseases and Injuries

The code E27.1 has the following ICD-10-CM references to the Index of Diseases and Injuries
  • Inclusion Terms:
    • Addison's disease
    • Autoimmune adrenalitis
  • Type 1 Excludes Notes:
    • Addison only phenotype adrenoleukodystrophy (@E71.528*)
    • amyloidosis (@E85*.-)
    • tuberculous Addison's disease (@A18.7*)
    • Waterhouse-Friderichsen syndrome (@A39.1*)

Crosswalk Information

ICD-10 Code ICD-9 Code ICD-9 Description
E27.1 Right Arrow 255.41 Glucocorticoid deficient

This ICD-10 to ICD-9 data is based on the 2018 General Equivalency Mapping (GEM) files published by the Centers for Medicare & Medicaid Services (CMS) for informational purposes only. The data is not an ICD-10 conversion tool and doesn’t guarantee clinical accuracy.

Similar Codes

ICD-10 Code ICD-10 Description
E27 Other disorders of adrenal gland
E27.0 Other adrenocortical overactivity
E27.2 Addisonian crisis
E27.3 Drug-induced adrenocortical insufficiency
E27.4 Other and unspecified adrenocortical insufficiency
E27.40 Unspecified adrenocortical insufficiency
E27.49 Other adrenocortical insufficiency
E27.5 Adrenomedullary hyperfunction
E27.8 Other specified disorders of adrenal gland
E27.9 Disorder of adrenal gland, unspecified

This page was last updated on: 10/1/2021