Diagnosis Code

M35.81 MULTISYSTEM INFLAMMATORY SYNDROME


Code Information

Diagnosis Code: M35.81

Short Description: Multisystem inflammatory syndrome

Long Description: Multisystem inflammatory syndrome

The code M35.81 is VALID for claim submission

Code Classification:

  • Diseases of the musculoskeletal system and connective tissue (M00–M99)
    • Systemic connective tissue disorders (M30-M36)
      • Other systemic involvement of connective tissue (M35)
        • M35.81 Multisystem inflammatory syndrome

Code Version: 2022 ICD-10-CM


Synonyms

  • Multisystem inflammatory syndrome in adults
  • Multisystem inflammatory syndrome in children
  • Systemic inflammatory response syndrome
  • Systemic inflammatory response syndrome

Diagnostic Related Group(s)

The code M35.81 is grouped in the following Diagnostic Related Group(s) (MS-DRG v39.0)
  • Connective Tissue Disorders With Mcc (545)
  • Connective Tissue Disorders With Cc (546)
  • Connective Tissue Disorders Without Cc/mcc (547)

References to Index of Diseases and Injuries

The code M35.81 has the following ICD-10-CM references to the Index of Diseases and Injuries
  • Inclusion Terms:
    • MIS-A
    • MIS-C
    • Multisystem inflammatory syndrome in adults
    • Multisystem inflammatory syndrome in children
    • Pediatric inflammatory multisystem syndrome
    • PIMS
  • Code First:
    • , if applicable, COVID-19 (U07.1)
  • Code Also:
    • any associated complications such as:
    • acute hepatic failure (@K72.0*-)
    • acute kidney failure (@N17*.-)
    • acute myocarditis (@I40*.-)
    • acute respiratory distress syndrome (@J80*)
    • cardiac arrhythmia (@I47*-@I49*.-)
    • pneumonia due to COVID-19 (@J12.82*)
    • severe sepsis (@R65.2*-)
    • viral cardiomyopathy (@B33.24*)
    • viral pericarditis (@B33.23*)

Similar Codes

ICD-10 Code ICD-10 Description
M35 Other systemic involvement of connective tissue
M35.0 Sjogren syndrome
M35.00 Sjogren syndrome, unspecified
M35.01 Sjogren syndrome with keratoconjunctivitis
M35.02 Sjogren syndrome with lung involvement
M35.03 Sjogren syndrome with myopathy
M35.04 Sjogren syndrome with tubulo-interstitial nephropathy
M35.05 Sjogren syndrome with inflammatory arthritis
M35.06 Sjogren syndrome with peripheral nervous system involvement
M35.07 Sjogren syndrome with central nervous system involvement
M35.08 Sjogren syndrome with gastrointestinal involvement
M35.09 Sjogren syndrome with other organ involvement
M35.0A Sjogren syndrome with glomerular disease
M35.0B Sjogren syndrome with vasculitis
M35.0C Sjogren syndrome with dental involvement
M35.1 Other overlap syndromes
M35.2 Behcet's disease
M35.3 Polymyalgia rheumatica
M35.4 Diffuse (eosinophilic) fasciitis
M35.5 Multifocal fibrosclerosis
M35.6 Relapsing panniculitis [Weber-Christian]
M35.7 Hypermobility syndrome
M35.8 Other specified systemic involvement of connective tissue
M35.89 Other specified systemic involvement of connective tissue
M35.9 Systemic involvement of connective tissue, unspecified


This page was last updated on: 10/1/2023