281.0 PERNICIOUS ANEMIA


Code Information

Diagnosis Code: 281.0

Short Description: Pernicious anemia

Long Description: Pernicious anemia

Code Classification:

  • Diseases of the blood and blood-forming organs (280–289)
    • Diseases of the blood and blood-forming organs (280-289)
      • 281 Other deficiency anemias
        • 281.0 Pernicious anemia

Code Version: 2015 ICD-9-CM


References to Index of Diseases and Injuries

The code 281.0 has the following ICD-9-CM references to the Index of Diseases and Injuries
  • Addison's
    • anemia (pernicious) 281.0
  • Addison-Biermer anemia (pernicious) 281.0
  • Anemia 285.9
    • Addison's (pernicious) 281.0
    • Addison-Biermer (pernicious) 281.0
    • Biermer's (pernicious) 281.0
    • combined system disease NEC 281.0 [336.2]
      • due to dietary deficiency 281.1 [336.2]
    • congenital (following fetal blood loss) 776.5
      • pernicious 281.0
    • cytogenic 281.0
    • deficiency 281.9
      • vitamin B12�NEC 281.1
        • pernicious 281.0
    • malignant (progressive) 281.0
    • pernicious (combined system disease) (congenital) (dorsolateral spinal degeneration) (juvenile) (myelopathy) (neuropathy) (posterior sclerosis) (primary) (progressive) (spleen) 281.0
      • of or complicating pregnancy 648.2
    • progressive 285.9
      • malignant 281.0
      • pernicious 281.0
    • vitamin
      • B12�deficiency (dietary) 281.1
        • pernicious 281.0
  • Biermer's anemia or disease (pernicious anemia) 281.0
  • Congenital - see also condition
    • intrinsic factor deficiency 281.0
  • Dana-Putnam syndrome (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
  • Deficiency, deficient
    • intrinsic factor (Castle's) (congenital) 281.0
  • Degeneration, degenerative
    • combined (spinal cord) (subacute) 266.2 [336.2]
      • with anemia (pernicious) 281.0 [336.2]
        • due to dietary deficiency 281.1 [336.2]
    • spinal (cord) 336.8
      • combined (subacute) (see also Degeneration, combined) 266.2 [336.2]
        • with anemia (pernicious) 281.0 [336.2]
  • Disease, diseased - see also Syndrome
    • Addison's (bronze) (primary adrenal insufficiency) 255.41
      • anemia (pernicious) 281.0
    • Biermer's (pernicious anemia) 281.0
    • combined system (of spinal cord) 266.2 [336.2]
      • with anemia (pernicious) 281.0 [336.2]
    • Lichtheim's (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
    • Putnam's (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
    • Runeberg's (progressive pernicious anemia) 281.0
    • spine, spinal 733.90
      • combined system (see also Degeneration, combined) 266.2 [336.2]
        • with pernicious anemia 281.0 [336.2]
  • Lichtheim's disease or syndrome (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
  • Myasthenia 358.00
    • syndrome
      • in
        • pernicious anemia 281.0 [358.1]
  • Myelopathy (spinal cord) 336.9
    • due to or with
      • pernicious anemia 281.0 [336.3]
  • Neuropathy, neuropathic (see also Disorder, nerve) 355.9
    • vitamin B12�266.2 [357.4]
      • with anemia (pernicious) 281.0 [357.4]
        • due to dietary deficiency 281.1 [357.4]
  • Putnam's disease (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
  • Putnam-Dana syndrome (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
  • Runeberg's disease (progressive pernicious anemia) 281.0
  • Syndrome - see also Disease
    • Dana-Putnam (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
    • Lichtheim's (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]
    • Putnam-Dana (subacute combined sclerosis with pernicious anemia) 281.0 [336.2]

Crosswalk Information

The code 281.0 converts into the following ICD-10 code(s):
ICD-9 Code ICD-10 Code ICD-10 Description
281.0 Right Arrow D51.0 Vitamin B12 defic anemia due to intrinsic factor deficiency
This ICD-9 to ICD-10 data is based on the 2018 General Equivalency Mapping (GEM) files published by the Centers for Medicare & Medicaid Services (CMS) for informational purposes only. The data is not an ICD-10 conversion tool and doesn’t guarantee clinical accuracy.

Similar Codes

ICD-9 Code ICD-9 Description
281.1 Other vitamin B12 deficiency anemia
281.2 Folate-deficiency anemia
281.3 Other specified megaloblastic anemias not elsewhere classified
281.4 Protein-deficiency anemia
281.8 Anemia associated with other specified nutritional deficiency
281.9 Unspecified deficiency anemia


This page was last updated on: 10/1/2014