Diagnosis Code

D81.82 ACTIVATED PHOSPHOINOSITIDE 3-KINASE DELTA SYNDROME [APDS]


Code Information

Diagnosis Code: D81.82

Short Description: Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

Long Description: Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

The code D81.82 is VALID for claim submission

Code Classification:

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Certain disorders involving the immune mechanism (D80-D89)
      • Combined immunodeficiencies (D81)
        • D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

Code Version: 2022 ICD-10-CM


Diagnostic Related Group(s)

The code D81.82 is grouped in the following Diagnostic Related Group(s) (MS-DRG v39.0)
  • Major Hematological And Immunological Diagnoses Except Sickle Cell Crisis And Coagulation Disorders With Mcc (808)
  • Major Hematological And Immunological Diagnoses Except Sickle Cell Crisis And Coagulation Disorders With Cc (809)
  • Major Hematological And Immunological Diagnoses Except Sickle Cell Crisis And Coagulation Disorders Without Cc/mcc (810)

References to Index of Diseases and Injuries

The code D81.82 has the following ICD-10-CM references to the Index of Diseases and Injuries
  • Inclusion Terms:
    • p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease
  • Code Also:
    • , if applicable, any associated manifestations, such as:
    • bronchiectasis (@J47*.-)
    • herpes virus infections (@B00*.-)
    • other acute respiratory tract infections (@J00*-@J06*; @J20*-@J22*)
    • other infections (@A00*-@B99*)
    • pneumonia (@J12*-@J18*)

Similar Codes

ICD-10 Code ICD-10 Description
D81 Combined immunodeficiencies
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D81.3 Adenosine deaminase [ADA] deficiency
D81.30 Adenosine deaminase deficiency, unspecified
D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency
D81.32 Adenosine deaminase 2 deficiency
D81.39 Other adenosine deaminase deficiency
D81.4 Nezelof's syndrome
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
D81.6 Major histocompatibility complex class I deficiency
D81.7 Major histocompatibility complex class II deficiency
D81.8 Other combined immunodeficiencies
D81.81 Biotin-dependent carboxylase deficiency
D81.810 Biotinidase deficiency
D81.818 Other biotin-dependent carboxylase deficiency
D81.819 Biotin-dependent carboxylase deficiency, unspecified
D81.89 Other combined immunodeficiencies
D81.9 Combined immunodeficiency, unspecified


This page was last updated on: 10/1/2023